Two Familial Mesothelioma Cases with High Concentrations of Soluble Cytokeratin 19 Fragment in Pleural Fluid.
- 1 January 1998
- journal article
- case report
- Published by Japanese Society of Internal Medicine in Internal Medicine
- Vol. 37 (4) , 407-410
- https://doi.org/10.2169/internalmedicine.37.407
Abstract
We report two cases of diffuse malignant pleural mesothelioma occurring almost simultaneously in one family. Patient 1 was a 42-year-old Japanese man who had worked as an electrical engineer for 25 years. Patient 2, his mother, was 69 years old. She lived for 10 years with patient 1 after he started his work, and also worked at a shipyard herself for 6 years. The concentrations of cytokeratin subunit 19 fragment (CYFRA 21-1) in pleural fluid of the two patients were 1,500 ng/ml, and 1,200 ng/ml, respectively. Measurement of CYFRA 21-1 concentration in the pleural fluid may be a useful tool for a diagnosis of malignant mesothelioma.Keywords
This publication has 0 references indexed in Scilit: