THE EFFECT OF EMOTIONAL-STRESS ON INTRAVASCULAR COAGULATION IN PATIENTS WITH ANGIOGRAPHIC EVIDENCE OF CORONARY-DISEASE

  • 1 January 1985
    • journal article
    • research article
    • Vol. 25  (2) , 34-38
Abstract
The effect of simulated emotional stress (ES) on the platelet/vascular and plasma components of the hemostatic system was examined in normal subjects and coronary patients. In coronary patients, pre-stress hemostatic platelet/vascular and plasma factors were disturbed, their blood showing a tendency to activated intravascular coagulation. Stress further increased the blood thrombogenic potential of coronary patients, causing intravascular coagulation as evidenced by declining cAMP/cHMP [cyclic hexose monophosphate] ratio, enhanced release of soluble fibrin and fibrinogen-fibrin degradation products (FDPs), and reduced antithrombin III.

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