Free radicals in Alzheimer’s dementia: currently available therapeutic strategies

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Abstract
Recent in vitro studies have demonstrated the efficacy of both types of therapeutic agents by preventing or delaying oxidative neural damage. Some clinical data exist regarding the antidementive properties particularly in terms of gingko biloba, selegiline and vitamin E. The efficacy studies about these compounds seem to indicate a promising future strategy in the therapy of DAT. But it is too early to draw definite conclusions since it is well kown that all of our candidate substances do not act specifically as radical scavengers or antioxidants.