Studies on Escherichia coli Enzymes Involved in the Synthesis of Uridine Diphosphate- N -Acetyl-Muramyl-Pentapeptide
- 1 April 1972
- journal article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 110 (1) , 26-34
- https://doi.org/10.1128/jb.110.1.26-34.1972
Abstract
The specific activities of l -alanine: d -alanine racemase, d -alanine: d -alanine ligase, and the l -alanine, d -glutamic acid, meso -diaminopimelic acid, and d -alanyl- d -alanine adding enzymes were followed during growth of Escherichia coli . The specific activities were nearly independent of the growth phase. d -Alanine: d -alanine ligase was inhibited by d -alanyl- d -alanine, d -cycloserine, glycine, and glycyl-glycine. l -Alanine: d -alanine racemase was found to be sensitive to d -cycloserine, glycine, and glycyl-glycine. The l -alanine adding enzyme was inhibited by glycine and glycyl-glycine.Keywords
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