A Stereoselective Synthesis of 5-Substituted 3-Methyltetronic Acid Derivatives1
- 1 January 1992
- journal article
- letter
- Published by Georg Thieme Verlag KG in Synlett
- Vol. 1992 (05) , 429-430
- https://doi.org/10.1055/s-1992-21370
Abstract
Chiral ethyl 3-lithio-2-methyl-3-(1-phenylethoxy)-acrylate (2) was reacted with various aldehydes leading to a stereoselective synthesis of structurally important tetronic acid derivatives 3a-f (5-substituted 3-methyl-4-(1-phenylethoxy)furan-2(5H)-ones].Keywords
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