Significance of autogenously regulated and constitutive synthesis of regulatory proteins in repressible biosynthetic systems
- 1 November 1975
- journal article
- Published by Springer Nature in Nature
- Vol. 258 (5532) , 208-214
- https://doi.org/10.1038/258208a0
Abstract
The functional implications of the different modes of regulation have been examined systematically. The results lead to certain predictions. The regulatory protein in repressor-controlled systems is constitutively synthesised. In activator-controlled systems synthesis of the regulatory protein is autogenously regulated. There is favourable agreement between these predictions and published experimental evidence.Keywords
This publication has 34 references indexed in Scilit:
- Genetic regulatory mechanisms in the synthesis of proteinsPublished by Elsevier ,2010
- Comparison of classical and autogenous systems of regulation in inducible operonsNature, 1974
- Repression of tryptophan operon RNA synthesis by trp repressor in an in vitro coupled transcription—translation systemFEBS Letters, 1974
- Synthesis of Tryptophan Operon RNA in a Cell-free SystemNature New Biology, 1973
- Regulation of in vitro Transcription of the Tryptophan Operon by Purified RNA Polymerase in the Presence of Partially Purified Repressor and TryptophanNature New Biology, 1973
- Tryptophanyl-tRNA and Tryptophanyl-tRNA Synthetase are not Required for in vitro Repression of the Tryptophan OperonNature New Biology, 1973
- In vitro repression of N-α-acetyl-L-ornithinase synthesis in Escherichia coliMolecular Genetics and Genomics, 1973
- THE OPERON REVISITEDAnnual Review of Genetics, 1972
- Detection and Isolation of the Repressor Protein for the Tryptophan Operon of Escherichia coliProceedings of the National Academy of Sciences, 1972
- Isolation of the Arginine Repressor in Escherichia coliNature, 1970