NATURAL ANTI-HLA-A2 ANTIBODY REACTING WITH HOMOZYGOUS CELLS

1 January 1976

journal article
research article

Vol. 8 (2) , 139-142

Abstract

In the serum of a young normal male, never transfused, a cold cytotoxic IgM [immunoglobulin M] antibody was found reacting exclusively with A2 homozygous cells on a French panel, as shown by population and family studies. This antibody needs about 2-5 times more lymphocytes or platelets to be absorbed than an immune anti-A2 of the same titer. The antigen recognized by this antibody seems to be covered by the same molecule as HL-A-A2, according to redistribution experiments.

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