Allelic frequencies of an ovine scrapie susceptibility gene
- 1 October 1996
- journal article
- research article
- Published by Taylor & Francis in Animal Biotechnology
- Vol. 7 (2) , 155-162
- https://doi.org/10.1080/10495399609525856
Abstract
The allelic frequencies of an ovine gene associated with susceptibility to scrapie was analyzed in a sample of 30 scrapie affected sheep and 545 clinically normal sheep from 12 flocks. The allele encoding glutamine at codon 171 occurred at a frequency of 0.76 in the overall population. All 30 scrapie affected sheep were homozygous for glutamine at codon 171. This genotype was observed in 56.5% of the clinically normal sheep. None of the 30 scrapie affected sheep carried the allele encoding Valine at codon 136 although this allele was observed in 2/12 flocks sampled.Keywords
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