Frur mediates catabolite activation of pyruvate kinase (pykF) gene expression in Escherichia coli
- 1 January 1996
- journal article
- research article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 178 (1) , 280-283
- https://doi.org/10.1128/jb.178.1.280-283.1996
Abstract
Expression of a pykF-lacZ fusion was studied as a function of the carbon source in wild-type strains and strains lacking or overproducing the FruR protein of Escherichia coli. FruR controls the response to the carbon source by repressing pykF expression more strongly under gluconeogenic than under glycolytic conditions, a phenomenon we term catabolite activation.Keywords
This publication has 15 references indexed in Scilit:
- The global regulatory protein FruR modulates the direction of carbon flow in Escherichia coliMolecular Microbiology, 1995
- In Vitro Binding of the Pleiotropic Transcriptional Regulatory Protein, FruR, to the fru, pps, ace, pts and icd Operons of Escherichia coli and Salmonella typhimuriumJournal of Molecular Biology, 1993
- The repressor of the PEP: Fructose phosphotransferase system is required for the transcription of the pps gene of Escherichia coliMolecular Genetics and Genomics, 1989
- Evidence for regulation of gluconeogenesis by the fructose phosphotransferase system in Salmonella typhimuriumJournal of Bacteriology, 1987
- Improved single and multicopy lac-based cloning vectors for protein and operon fusionsGene, 1987
- Relationship between pseudo-HPr and the PEP: fructose phosphotransferase system in Salmonella typhimurium and Escherichia coliMolecular Genetics and Genomics, 1986
- Transfer of the Δ (argF-lac) U169 mutation between Escherichia coli strains by selection for a closely linked Tn10 insertionMolecular Genetics and Genomics, 1983
- Pedigrees of some mutant strains of Escherichia coli K-12.1972
- Intermediary Metabolite Levels in Escherichia coliJournal of General Microbiology, 1972
- The Effect of Carbon and Nitrogen Sources on the Level of Metabolic Intermediates in Escherichia coliJournal of Biological Chemistry, 1971