Allgemeine Regulation der Aminosäurebiosynthese inHansenula henricii
- 1 January 1981
- journal article
- abstracts
- Published by Wiley in Journal of Basic Microbiology
- Vol. 21 (10) , 705-713
- https://doi.org/10.1002/jobm.3630211002
Abstract
The general control of amino acid biosynthesis was investigated in Hansenula henricii. By limitation for single amino acids in wild type strain and mutants no derepression of enzymes was caused. In prototrophic revertants however, obtained from auxotrophic mutants (his, pdx) enzyme activities were 2 - 17 times higher than in the wild type. In these revertants enzymes of the biosynthetic pathways for tryptophan, phenylalanine, tyrosine, arginine, histidine, cysteine, methionine, asparagine, threonine, and isoleucine were derepressed. The amino acid pool pattern of the revertants if completely different from that in the wild type strain. A discussion of possible mechanisms of general control of amino acid biosynthesis in H. henricii is presented.Keywords
This publication has 11 references indexed in Scilit:
- Regulation of Protein Synthesis in EukaryotesAnnual Review of Biochemistry, 1979
- Die Formamidase von Hansenula henricii: Isolierung, Charakterisierung und Regulation multipler FormenBiochemie und Physiologie der Pflanzen, 1979
- Concerted repression of the synthesis of the arginine biosynthetic enzymes by aminoacids: A comparison between the regulatory mechanisms controlling aminoacid biosyntheses in bacteria and in yeastMolecular Genetics and Genomics, 1979
- Die Enzyme der Biosynthese aromatischer Aminosäuren beiHansenula henricii: Nachweis und Charakterisierung der Enzyme des Pretyrosin-WegesJournal of Basic Microbiology, 1979
- Post-Transcriptional and Translational Controls of Gene Expression in EukaryotesAnnual Review of Biochemistry, 1978
- Die Enzyme der Biosynthese aromatischer Aminosäuren bei Hansenula henricii : Die AminotransferasenBiochemie und Physiologie der Pflanzen, 1978
- Guanosine 5'-diphosphate 3'-diphosphate (ppGpp): positive effector for histidine operon transcription and general signal for amino-acid deficiency.Proceedings of the National Academy of Sciences, 1975
- The Regulation of Arginine Biosynthesis in Saccharomyces cerevisiae. The Specificity of argR- Mutations and the General Control of Amino-Acid BiosynthesisEuropean Journal of Biochemistry, 1975
- Cross pathway regulation of tyrosine and histidine synthesis in Bacillus subtilisBiochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1974
- Regulation and Characterization of Acid and Alkaline Phosphatase in YeastJournal of General Microbiology, 1971