PULMONARY-FUNCTION IN IDENTICAL-TWINS - COMPARISON OF NON-SMOKERS AND SMOKERS

1 January 1979

journal article
research article
Published by Elsevier

Vol. 119 (2) , 223-228
https://doi.org/10.1164/arrd.1979.119.2.223

Abstract

Apparently normal pairs of identical twins (45) were given pulmonary function tests to determine the role of genetics in bronchial susceptibility to cigarette smoke. Maximal expiratory flow at 60% of total lung capacity (.ovrhdot.Vmax60) was the best discriminator of smokers from nonsmokers among pairs in which one member smoked and the other did not. The intrapair difference of .ovrhdot.Vmax60 values in pairs in which both members smoked was the same as in pairs in which both members did not smoke. Genetic factors are apparently important in determining the vulnerability of the airways to cigarette smoke.

This publication has 4 references indexed in Scilit:

RELATIONSHIP OF CHILDHOOD RESPIRATORY ILLNESS TO ADULT OBSTRUCTIVE AIRWAY DISEASE
Published by Elsevier ,1977
Genetic influence on normal variability of maximum expiratory flow-volume curves
Journal of Applied Physiology, 1976
COMPARISON OF PULMONARY-FUNCTION IN MALE SMOKERS AND NONSMOKERS
Published by Elsevier ,1976
Morphologic Constitution and Smoking
JAMA, 1963