New high yield Cu(I) assisted 123I radioiodination of 15(p-I-phenyl)-9-methyl pentadecanoic acid, a potential myocardial tracer
- 1 June 1987
- journal article
- research article
- Published by Springer Nature in European Journal of Nuclear Medicine and Molecular Imaging
- Vol. 13 (3) , 159-160
- https://doi.org/10.1007/bf00289030
Abstract
A new high yield 123I radioiodination (97%), based on the Cu(I) assisted isotopic exchange in an ethanol water mixture, of 15(p-I-phenyl)-9 methyl pentadecanoic acid, a potential myocardial tracer, is proposed. The method allows a true kit preparation of radioiodinated phenyl fatty acids for a substrate concentration of ±10-6 moles. High specific activities (>0.1 mCi/μg) can be obtained when coupling the labelling method to HPLC purification with an overall radiochemical yield of 75%.This publication has 5 references indexed in Scilit:
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