BRNO‐I, An Implantable, Diaphragm‐Type Total Artificial Heart: Technical Aspects of Design

Abstract
The technical aspects of artificial heart design for experiments on calves are presented. The object of the design was to verify the basic anatomic and hemodynamic criteria for the design of more perfect cardiac prostheses. Each ventricle has a 100-ml stroke volume and is dismountable. Rigid parts are made of polymethylmethacrylate. The inlet valve has the shape of a flap. The outlet valve has 2 polyurethane reinforcing leaves. The diaphragm is made of polyurethane. During tests using artificial circulation a maximum cardiac output of 14.6 l/min was achieved. Typical sensitivity of flow on the atrial pressure is 0.3 l/min per torr at a frequency of 90 pulses/min.

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