Abstract
Pituitary tumors were induced in mice by single exposure to ionizing radiation. The greatest incidence occurred among mice exposed to doses of gamma radiation somewhat below the LD50. These tumors were about 4 times more frequent among females than among males. Neutrons appear to be more efficient in inducing these neoplasms than gamma rays; doses as low as 40-70 rem may induce such tumors. The latent period for these neoplasms is very long, the max. incidence occurring 17-25 mos. postirradiation.

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