Inheritance of reaction to halothane anaesthesia in pigs
- 14 April 1977
- journal article
- research article
- Published by Hindawi Limited in Genetics Research
- Vol. 29 (3) , 287-292
- https://doi.org/10.1017/s0016672300017365
Abstract
SUMMARY: The inheritance of reaction to halothane anaesthesia (so-called malignant hyperthermia syndrome) in pigs was studied in a series of 61 litters by 18 sires from an F3–F4 Pietrain–Hampshire crossbred population. A single locus two allele model allowing for reactors from all three genotypes, was fitted by maximum likelihood. It was concluded that the reaction is due to a single autosomal recessive gene with a frequency of 0·46 (0·44–0·48) and penetrance of 0·95 (0·92–0·98) in this stock.This publication has 5 references indexed in Scilit:
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