The remarkable improvements in survival at older ages
Open Access
- 29 December 1997
- journal article
- review article
- Published by The Royal Society in Philosophical Transactions Of The Royal Society B-Biological Sciences
- Vol. 352 (1363) , 1799-1804
- https://doi.org/10.1098/rstb.1997.0164
Abstract
The belief that old–age mortality is intractable remains deeply held by many people. Remarkable progress, however, has been made since 1950, and especially since 1970, in substantially improving survival at older ages, even the most advanced ages. The pace of mortality improvement at older ages continues to be particularly rapid in Japan, even though mortality levels in Japan are lower than elsewhere. The progress in improving survival has accelerated the growth of the population of older people and has advanced the frontier of human survival substantially beyond the extremes of longevity attained in pre–industrial times. Little, however, is known about why mortality among the oldest–old has been so plastic since 1950. The little that is known has largely been learned within the past few years. New findings, especially concerning genetic factors that influence longevity, are emerging at accelerating rate.Keywords
This publication has 18 references indexed in Scilit:
- No Increased Mortality in Later Life for Cohorts Bom during FamineAmerican Journal of Epidemiology, 1997
- Determinants of longevity: genetic, environmental and medical factorsJournal of Internal Medicine, 1996
- Survival after the Age of 80 in the United States, Sweden, France, England, and JapanNew England Journal of Medicine, 1995
- Fetal origins of coronary heart diseaseBMJ, 1995
- Mortality among twins after age 6: fetal origins hypothesis versus twin methodBMJ, 1995
- Reductions in Mortality at Advanced Ages: Several Decades of Evidence from 27 CountriesPopulation and Development Review, 1994
- Genetic associations with human longevity at the APOE and ACE lociNature Genetics, 1994
- Choosing the limits to lifeNature, 1992
- In Search of Methuselah: Estimating the Upper Limits to Human LongevityScience, 1990
- DEATH-RATES IN GREAT BRITAIN AND SWEDEN SOME GENERAL REGULARITIES AND THEIR SIGNIFICANCEThe Lancet, 1934