Treatment of Brucellosis in Humans

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Abstract
Brucellosis in humans can be a self-limiting illness, with recovery expected within a year even without specific therapy. 1 Nevertheless, the morbidity associated with brucellosis is considerable, especially infections caused by Brucella melitensis, and complications are serious and may be life-threatening. Specific therapy reduces morbidity, shortens the duration of illness, and decreases the incidence of complications. Treatment of serious complications, such as meningitis and endocarditis is life saving. In the pre-antibiotic era treatment consisted of the injection of serum and antigens, or drugs such as neoarsphenamine and sulfanilamide. 2 With the advent of antibiotics such as streptomycin and aureomycin the effective chemotherapy of brucellosis became a reality.

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