Intrinsic and Intramolecular Lipophilicity Effects in O‐Glucuronides
- 4 February 1998
- journal article
- medicinal and-biological-chemistry
- Published by Wiley in Helvetica Chimica Acta
- Vol. 81 (2) , 330-341
- https://doi.org/10.1002/hlca.19980810214
Abstract
No abstract availableKeywords
This publication has 41 references indexed in Scilit:
- Morphine-6-glucuronide, a potent mu agonistPublished by Elsevier ,2002
- Structural Properties Governing Retention Mechanisms on RP-HPLC Stationary Phases Used for Lipophilicity MeasurementsJournal of Liquid Chromatography, 1995
- Rat serum albumin modified by diflunisal acyl glucuronide is emmunogenic in ratsLife Sciences, 1995
- Morphine and morphine metabolite kinetics in the rat brain as assessed by transcortical microdialysisLife Sciences, 1994
- The conformation-dependent lipophilicity of morphine glucuronides as calculated from their molecular lipophilicity potentialBioorganic & Medicinal Chemistry Letters, 1994
- CSF and plasma concentrations of morphine and morphine glucuronides in cancer patients receiving epidural morphinePain, 1993
- Morphine-3-glucuronide - a potent antagonist of morphine analgesiaLife Sciences, 1990
- Morphine-6-glucuronide: Analgesic effects and receptor binding profile in ratsLife Sciences, 1988
- Enhanced binding of morphine and nalorphine to opioid delta receptor by glucuronate and sulfate conjugations at the 6-positionLife Sciences, 1987
- Conjugation Reactions in Foreign-Compound Metabolism: Definition, Consequences, and Species VariationsDrug Metabolism Reviews, 1982