Transport of 2-deoxy-D-glucose by isolated protoplasts of the yeast, Kluyveromyces lactis

Abstract
Protoplasts of succinate- and glucose-grown Kluyveromyces lactis were generated by incubating cells with β-mercaptoethanol and β-glucuronidase in the presence of MgSO4 as osmotic stabilizer. Transport of 2-deoxyglucose by the protoplasts was comparable with that of the walled cells. Only protoplasts of succinate-grown cells exhibited a lag in glucose utilization. Removal of the wall by this technique does not result in loss of the inducible component of the glucose carrier via degradation or release.

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