The synthesis of highly phosphorylated nucleotides, RNA and protein by Streptomyces aureofaciens.
- 1 January 1979
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 32 (1) , 53-58
- https://doi.org/10.7164/antibiotics.32.53
Abstract
During the sudden decrease in RNA synthesis in S. aureofaciens, i.e., around the 6th h of cultivation, synthesis of adenosine and guanosine tetraphosphates and pentaphosphates begins. The synthesis of these nucleotides is highest during the onset of chlortetracycline (CTC) production around the 20th h of cultivation and continues. During this phase of growth of S. aureofaciens, RNA and protein synthesis are reduced by about 1 order of magnitude as compared to the rate which can be observed at the beginning of cultivation but the synthesis is not inhibited by exogenous CTC.This publication has 1 reference indexed in Scilit:
- Tetracycline Inhibition of Cell-Free Protein Synthesis I. Binding of Tetracycline to Components of the SystemJournal of Bacteriology, 1966