Comparative Evaluation of Therapeutic Response to Antiasthma Drugs: Dry Powder vs. Conventional Aerosol Delivery Systems
- 1 January 1996
- journal article
- research article
- Published by Mary Ann Liebert Inc in Journal of Aerosol Medicine
- Vol. 9 (1) , 89-94
- https://doi.org/10.1089/jam.1996.9.89
Abstract
Dry powder inhaler (DPI) delivery systems provide advantages over the metered-dose inhaler (MDI) systems. Of the anti-asthma agents studied, most of the trials have focused on the beta adrenergic agonists with a lesser degree of inhaled cromoglycate and corticosteroids. The results of the studies show either similarities or a lesser effect on pulmonary function for the DPI systems but, in most cases, clinical symptoms are comparable. The trials reported vary in the type of controlled designs, doses, and systems evaluated, hence scrutiny of resultant data should follow assessment of methodology in order to clinically interchange these systems in asthmatic patients.Keywords
This publication has 18 references indexed in Scilit:
- Terbutaline via pressurised metered dose inhaled (P-MDI) and Turbuhaler in highly reactive asthmatic patientsEuropean Respiratory Journal, 1994
- Terbutaline inhalations by the turbuhaler® as replacement for domiciliary nebulizer therapy in severe chronic obstructive pulmonary diseaseRespiratory Medicine, 1994
- Evaluation of fluticasone propionate (500 μg day−1) administered either as dry powder via a Diskhaler® inhaler or pressurized inhaler and compared with beclomethasone dipropionate (1000 μg day−1) administered by pressurized inhalerRespiratory Medicine, 1993
- A Single-dose Comparison of Inhaled Albuterol and Two Formulations of Salmeterol on Airway Reactivity in Asthmatic SubjectsAmerican Review of Respiratory Disease, 1991
- A multicenter evaluation of the clinical benefits of cromolyn sodium aerosol by metered-dose inhaler in the treatment of asthmaJournal of Allergy and Clinical Immunology, 1988
- A Clinical Comparison of Aerosol and Powder Administration of Beclomethasone Dipropionate in Childhood AsthmaAllergy, 1984
- Comparison of sodium cromoglycate pressurized aerosol and powder in the treatment of asthmaClinical and Experimental Allergy, 1982
- Long-term comparison of salbutamol powder with salbutamol aerosol in asthmatic out-patientsRespiratory Medicine, 1979
- Use of salbutamol powder in childhood asthma.Archives of Disease in Childhood, 1978
- COMPARISON OF THE BRONCHODILATOR EFFECTS OF SALBUTAMOL INHALED AS A DRY POWDER AND BY CONVENTIONAL PRESSURISED AEROSOLPublished by Wiley ,1977