Regional Distribution of Calmodulin Activity in Rat Brain
- 1 May 1985
- journal article
- Published by Wiley in Journal of Neurochemistry
- Vol. 44 (5) , 1657-1662
- https://doi.org/10.1111/j.1471-4159.1985.tb08809.x
Abstract
Calmodulin activity in 68 discrete areas of rat brain, obtained by micropunch technique, was assessed by its capacity to activate a calmodulin‐sensitive form of phosphodiesterase. In general, the activity of calmodulin was higher in the telencephalon, limbic system, and hypothalamus than in the mesencephalon, pons, cerebellum, and medulla. However, there were substantial differences in calmodulin activity in discrete nuclei of each region. The regional distribution of calmodulin activity in rat brain does not appear to correlate with that of any of the known putative neurotransmitters or peptides.Keywords
This publication has 49 references indexed in Scilit:
- Regulation of Calmodulin‐ and Dopamine‐Stimulated Adenylate Cyclase Activities by Light in Bovine RetinaJournal of Neurochemistry, 1984
- Influence of temperature and denaturing agents on the structural stability of calmodulinFEBS Letters, 1983
- Inhibition by Quinacrine of Depolarization-Induced Acetylcholine Release and Calcium Influx in Rat Brain Cortical SynaptosomesJournal of Neurochemistry, 1983
- Catencholamine neuron systems in brainAnnals of Neurology, 1982
- Most of the Ca2+-dependent endogenous phosphorylation of rat brain cytosol proteins requires Ca2+-dependent regulator proteinBiochemical and Biophysical Research Communications, 1979
- Activation of tryptophan 5-monooxygenase by calcium-dependent regulator proteinBiochemical and Biophysical Research Communications, 1979
- Occurrence of A Ca2+ ‐ and modulator protein‐activatable ATPase in the synaptic plasma membranes of brainFEBS Letters, 1979
- Topographic atlas of catecholamine and acetylcholinesterase‐containing neurons in the rat brain. II. Hindbrain (mesencephalon, rhombencephalon)Journal of Comparative Neurology, 1974
- Topographic atlas of catecholamine and acetylcholinesterase‐containing neurons in the rat brain. I. Forebrain (telencephalon, diencephalon)Journal of Comparative Neurology, 1974
- Calcium dependent phosphodiesterase activity and its activating factor (PAF) from brainBiochemical and Biophysical Research Communications, 1970