Rate of Exchange of Sodium and Potassium Between Amniotic Fluid and Maternal System.

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Abstract
The exchange rate of Na to and from the amniotic fluid was determined by the simultaneous application of Na-22 and Na-24. This was found to be 15 and 16 meq. of Na/hour, respectively. The rate of transfer of H2> Na, and K from the amniotic fluid to the maternal system was determined by the simultaneous application of tracers for each of these elements. The disappearance constants for Na and K were found to be nearly equal, indicating that the same percentage of these elements is exchanged/unit time, while that for deuterium was found to be 5 times as great. The exchange rates were calculated as 31.9 moles of water, 0.014 mole of Na, and 0.00041 mole of K/hour. It is concluded that the water and electrolytes of the amniotic fluid are in dynamic equilibrium with the maternal plasma, each exchanging at its own characteristic rate.

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