Measures Used in the Prevention and Treatment of Cardiac Arrhythmias

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Abstract
Quinidine (and Other Cinchona Alkaloids)Quinidine is of recognized value in the prevention and treatment of various cardiac arrhythmias, such as paroxysmal ventricular tachycardia and paroxysmal auricular fibrillation. However, there is considerable disagreement about the exact indications and contraindications, the nature and frequency of toxic reactions, the routes of administration and the dosage schedules of the drug. Since there is so much confusion surrounding the use of quinidine, the pertinent available information has been assembled and is discussed in some detail. Physiologic Disposition Knowledge of the fate of quinidine in man has been obtained by sensitive, accurate and specific analytical . . .

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