Plasma Glucose Clearance and Insulin Response in Cows with Abomasal Displacement*
- 12 February 1988
- journal article
- Published by Wiley in Journal of Veterinary Medicine Series A
- Vol. 35 (1-10) , 221-228
- https://doi.org/10.1111/j.1439-0442.1988.tb00026.x
Abstract
Summary: Animals with abomasal displacement showed higher basal blood glucose levels than control animals independent of their ketotic status. Glucose clearance after an intravenous glucose tolerance test (IVGTT) was delayed in these patients despite a high and long lasting insulin response.Attention was drawn to urinary glucose losses after IVGTT in cows, due to the low renal threshold. This causes an overestimation of glucose halflife of about 20 % during the hyperglycaemic period.Zusammenfassung: Plasma‐Glucose‐Clearance und Insulinantwort bei Kühen mit LabmagenverlagerungTiere mit Labmagenverbgerung zeigten unabhängig vom Ketose‐Status einen höheren basalen Blutglucosespiegel als Kontrolltiere. Die Glucose‐Clearance erfolgte bei einem intravenösen Glucose‐Toleranztest (IVGTT) bei den Patienten trotz lang andauernder Insulinantwort verzögert.Beim IVGTT wurden die auf die niedrige Nierenschwelle zurückzuführenden Glucoseverluste über den Harn berücksichtigt, die während der Hyperglycämie eine Überschätzung der biologischen Halbwertzeit von Glucose um etwa 20 % bedingten.Keywords
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