Structure and Antimicrobial Activity of Diterpenes from the Roots of Plectranthus hereroensis

1 June 1994

journal article
Published by American Chemical Society (ACS) in Journal of Natural Products

Vol. 57 (6) , 858-861
https://doi.org/10.1021/np50108a031

Abstract

Two abietane-type diterpenoids have been isolated from the roots of Plectranthus hereroensis (Labiatae), one being the already known horminone [1] and the other a new substance, 7 alpha,12-dihydroxy-17(15-->16)-abeo-abieta-8,12,16-triene-11 ,14-dione [2], whose structure was established by spectroscopic means. Compounds 1 and 2 showed antimicrobial activity against Staphylococcus aureus, Vibrio cholerae, Candida albicans, and Pseudomonas aeruginosa.

Keywords

STRUCTURE
ANTIMICROBIAL ACTIVITY
PLECTRANTHUS HEREROENSIS
CANDIDA ALBICANS
TYPE DITERPENOIDS
TWO ABIETANE
ABEO ABIETA
VIBRIO CHOLERAE
STAPHYLOCOCCUS AUREUS

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