SMOKING AND INVASIVE CERVICAL CANCER RISK

Publisher Website
Google Scholar
Abstract
The association between cigarette smoking and risk of invasive cervical cancer was investigated in a case-control study conducted in four hospitals in Leipzig, German Democratic Republic in 1983–1985. Analyses were based on 225 women aged 64 years or younger with newly diagnosed invasive cervical cancer and 435 age-matched controls with orthopedic or skin diseases. The crude relative risk of invasive cervical cancer was significantly elevated for women who had ever smoked (relative risk (RR) = 1.5, 95% confidence interval (Cl) =1.1−2.1). Adjustment for number of sexual partners reduced the risk to RR = 1.2 (95% Cl = 0.8− 1.6). Furthermore, the risk for smokers depended significantly on number of sexual partners (p < 0.05) and was increased only among women with no partner or one partner (RR = 2.7, 95% Cl = 1.2−6.1).