TREATMENT OF INFLUENZAL MENINGITIS WITH SULFADIAZINE

Abstract
Recent advances in chemotherapy have opened a more hopeful outlook on the treatment of bacterial meningitis. The usual failure of influenzal meningitis to respond favorably to the sulfonamide drugs that have been employed stands in sharp contrast to numerous recoveries which have been reported following the chemotherapy of other forms of purulent meningeal infection. It is true that sulfanilamide and sulfapyridine, used either alone or in conjunction with antiserum, have produced isolated cures, but Aleman,1who has recently reviewed the literature and her clinical experience with influenzal meningitis, stated: "Every form of treatment reported in the literature is discounted by those who have seen failures, and by actual statistics where a large number have been reported." Although anti-influenzal horse and rabbit serums have improved the prognosis of influenzal meningitis, data collected from the literature do not permit us to regard these serums with enthusiasm. The efficacy of the new