Androgen Effects on Rat Leydig Cells
- 1 March 1979
- journal article
- research article
- Published by Oxford University Press (OUP) in Biology of Reproduction
- Vol. 20 (2) , 304-309
- https://doi.org/10.1095/biolreprod20.2.304
Abstract
Treatment of hypophysectomized, 30-day-old male rats with 5 mg dihydrotestosterone propionate (DHTP) or testosterone propionate (TP) daily for 5-6 days resulted in a marked reduction in the magnitude of the maximum steroidogenic response of Leydig cells to hCG. This effect was not mediated through alterations in the LH receptor binding to testicular particles and did not represent a direct competitive inhibition of the steroidogenic enzymes.This publication has 5 references indexed in Scilit:
- Age-related changes in responsiveness of rat Leydig cells to hCGReproduction, 1978
- Hormonal regulation of testicular luteinizing hormone receptors. Effects on cyclic AMP and testosterone responses in isolated Leydig cells.Journal of Biological Chemistry, 1977
- Prolactin binding in rat testis: Specific receptors in interstitial cellsMolecular and Cellular Endocrinology, 1977
- HYPOTHALAMIC, PITUITARY AND TESTICULAR FUNCTION DURING SEXUAL MATURATION OF THE MALE RATJournal of Endocrinology, 1977
- Regulation of luteinizing hormone receptors in testicular interstitial cells by gonadotropinBiochemical and Biophysical Research Communications, 1976