THE RADIOGRAPHIC MANIFESTATIONS OF AMYLOIDOSIS

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Abstract
Amyloidosis is a multiple system disease which may occur primarily, either sporadically or as part of a heredofamilial disease, or secondarily in association with a wide variety of inflammatory and neoplastic disorders, including Hodgkin’s disease and renal cell carcinoma. At present, aging, rheumatoid arthritis, paraplegia, multiple myeloma and plasma cell dyscrasias appear to be the most frequent concomitants of amyloidosis. Radiographic manifestations of amyloid may be seen in the heart, lungs, kidneys, spleen, liver, gastrointestinal tract, subcutaneous tissues, bones and joints. Although the roentgen findings are not pathognomonic, they can be suggestive or corroborative, particularly in the presence of an associated secondary disease. Conversely, roentgen findings consistent with amyloidosis should promote search for an accompanying disorder.

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