Improved Nucleophilic Displacements in N-Methyl Pyrrolidinone as a Solvent
- 1 January 1989
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 19 (1) , 179-188
- https://doi.org/10.1080/00397918908050968
Abstract
The nucleophilic displacement reactions of 2- and 4- halogenonaphthalic-1,8, anhydrides and the N-imides, of 4,7- dichloroquinolines, the alkylation of lithio alkynes, the methylation of ethyl or methyl diacetylacetate and a variety of related reactions are greatly facilitated in N-methylpyrrolidinone as aprotic solvent.Keywords
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