Chemistry of the phenoxathiins i. Synthesis of 1‐azaphenoxathiin analogs as potential new CNS depressant agents
- 1 October 1977
- journal article
- research article
- Published by Wiley in Journal of Heterocyclic Chemistry
- Vol. 14 (6) , 1067-1069
- https://doi.org/10.1002/jhet.5570140624
Abstract
The condensation of the disodium salt of 2‐mercapto‐3‐pyridinol with various ortho‐nitrohalo‐benzenes to yield a group of previously unreported 1‐azaphenoxathiins is described. The synthetic pathway and the substituent location on the products is unequivocably demonstrated by Fourier Transform1 3 C‐nmr. Preliminary pharmacologic evaluation of the title compounds as potential CNS depressant agents is also reported.This publication has 8 references indexed in Scilit:
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