More than one DNA sequence encodes the 2''-O-adenylyltransferase phenotype
- 1 April 1987
- journal article
- research article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 31 (4) , 667-670
- https://doi.org/10.1128/aac.31.4.667
Abstract
Biochemical and phenotypic assays indicate that three enterobacterial R plasmids isolated in a single hospital encode 2''-O-adenylyltransferase [ANT(2'')], and an ANT(2'')-specific probe was developed from one plasmid. Southern hybridization revealed the three plasmids to be unrelated and, further, showed their ANT(2'')-encoding genes to be different.This publication has 18 references indexed in Scilit:
- Detection of specific sequences among DNA fragments separated by gel electrophoresisPublished by Elsevier ,2006
- Intercontinental Spread of a New Antibiotic Resistance Gene on an Epidemic PlasmidScience, 1985
- Development of a DNA Probe for the Structural Gene of the 2''-O-Adenyltransferase Aminoglycoside-Modifying EnzymeThe Journal of Infectious Diseases, 1984
- Analysis of gene control signals by DNA fusion and cloning in Escherichia coliJournal of Molecular Biology, 1980
- Physical Characterization of Ten R Plasmids Obtained from an Outbreak of Nosocomial Klebsiella pneumoniae InfectionsAntimicrobial Agents and Chemotherapy, 1979
- Nosocomial Multiply Resistant Klebsiella pneumoniae : Epidemiology of an Outbreak of Apparent Index Case OriginAntimicrobial Agents and Chemotherapy, 1979
- Plasmid-Determined Resistance to Antimicrobial AgentsAnnual Review of Microbiology, 1978
- Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase IJournal of Molecular Biology, 1977
- R‐factor mediated gentamicin resistance: A new enzyme which modifies aminoglycoside antibioticsFEBS Letters, 1971
- Determination of the base composition of deoxyribonucleic acid from its thermal denaturation temperatureJournal of Molecular Biology, 1962