The non-identity of Thudichum's ‘glycoleucine’ and norleucine
- 1 January 1945
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 39 (3) , 251-258
- https://doi.org/10.1042/bj0390251
Abstract
Thudichum"s original specimens of "glycoleucine", the amino-aeid isolated by him in 1882 from the proteins of brain, have been examined (a) for optical activity, (b) by partition chromatography, (c) by treatment with l-amino-acid oxidases of Proteus vulgaris and Penicillium roqueforti, and (d) by the prepn. of acetyl derivatives. They were found conclusively to consist of dl-leucine, not nor-leucine as hitherto assumed. Reinvestigation by partition chromatography of the acid hydrolysate of ox spinal cord indicated the absence of nor-leucine.This publication has 1 reference indexed in Scilit:
- Nachweis von l-(+)-Norleucin als Baustein von Proteinen des Rückenmarks und ferner peripherer Nerven.Hoppe-Seyler´s Zeitschrift Für Physiologische Chemie, 1933