Hepatoblastoma and low birth weight: A trend or chance observation?

Abstract
Background Several reports have suggested an association between prematurity and hepatoblastoma (HB). Procedure Data were collected by questionnaires from 105 children with HB enrolled in a Children's Cancer Group (CCG) study. Results Observed over expected rates were increased about 2− and 15+‐fold for prematurity (<37 weeks at birth) and low birth weight (<1,000 g) respectively. Similar data were derived from a later CCG study of 36 HB children. Conclusions Early reports of a possible association between prematurity and HB have been confirmed. Med Pediatr Oncol 2002;39:508–509.