Vagus nerve stimulation for epilepsy: Randomized comparison of three stimulation paradigms
- 26 July 2005
- journal article
- research article
- Published by Wolters Kluwer Health in Neurology
- Vol. 65 (2) , 317-319
- https://doi.org/10.1212/01.wnl.0000168899.11598.00
Abstract
Vagus nerve stimulation (VNS) is an effective adjunctive treatment for intractable epilepsy. However, the optimal range of device duty-cycles [on/(on + off times)] is poorly understood. The authors performed a multicenter, randomized trial of three unique modes of VNS, which varied primarily by duty-cycle. The results indicate that the three duty-cycles were equally effective. The data support the use of standard duty-cycles as initial therapy.Keywords
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