Hormones and electrolytes in premenstrual syndrome

Publisher Website
Google Scholar
Abstract
Ten normal and asymptomatic patients with ovulatory cycles were studied and serum Na, K, FSH, LH [luteinizing hormone], prolactin, estradiol, progesterone and cortisol were measured. The findings were compared with the levels in 25 patients with ovulatory cycles with premenstrual symptoms (PMS) lasting for 7-14 days prior to the onset of menstrual flow. No significant difference in serum Na and K levels was found between the asymptomatic (control) group and the PMS group, or between the follicular and luteal phases of the menstrual cycle. No difference was found in hormone levels other than an altered estrogen/progesterone ratio in the 2nd half of the luteal phase in 7 out of 12 PMS patients with severe symptoms and a higher level of cortisol in the luteal phase in 6 out of 12 patients with severe PMS symptoms. However, the level of serum cortisol was still within the normal range. There was no significant alteration in the levels of electrolytes or hormones during treatment with Navidrex K (cyclopenthiazide, diuretic), pyridoxine (vitamin B-6), dydrogesterone (Duphaston) alone, or all the 3 drugs combined.

This publication has 19 references indexed in Scilit: