SHOCK DUE TO ELECTRICAL INJURY IN FROGS

Abstract
Shock may be caused by giving electrical injury to a restricted region of the frog. If either the brain or the legs are subjected to alternating currents strong enough to cause injury (but not excessive heat) the animals show obvious shock. A circulating toxic factor is involved, for ligature of the legs prevents shock in frogs the legs of which are exposed to electrical injury. The toxic factor is apparently of the nature of a thrombin or thromboplastin. This is indicated by the changes which occur in the coagulation time of the blood of shocked animals. The first change is a slight decrease of coagulation time and this is followed by an increase.

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