Monosomy 12p in a radiation-induced germ cell tumor
- 1 September 1990
- journal article
- research article
- Published by Wiley in Genes, Chromosomes and Cancer
- Vol. 2 (3) , 186-190
- https://doi.org/10.1002/gcc.2870020304
Abstract
We report results of cytogenetic analysis of a cell line established from a radiation induced germ cell tumor. Tumors of this type are rare, and there is only one other report of chromosome analyses of solid tumors induced by radiotherapy (Cowan et al., 1990). The cells were grown for over a year, and harvested at passage 13. The karyotype was pseudodiploid, with several balanced translocations. Spontaneously occurring germ cell tumors are associated with i(12p). We did not observe an i(12p), but instead found monosomy of 12p and 7q22→q32.This publication has 40 references indexed in Scilit:
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