The Uncoupling Protein 2 Ala55Val Polymorphism Is Associated with Diabetes Mellitus: The CARDIA Study
- 1 August 2005
- journal article
- Published by Oxford University Press (OUP) in Clinical Chemistry
- Vol. 51 (8) , 1451-1456
- https://doi.org/10.1373/clinchem.2004.044859
Abstract
Background: Uncoupling proteins (UCPs) reduce ATP generation with concomitant increased release of heat. The activities of UCPs have been related to obesity and energy metabolism.Keywords
This publication has 28 references indexed in Scilit:
- Mitochondrial Dysfunction and Type 2 DiabetesScience, 2005
- Plasma F2-Isoprostanes and Coronary Artery Calcification: The CARDIA StudyClinical Chemistry, 2005
- Serum adiponectin in young adults—interactions with central adiposity, circulating levels of glucose, and insulin resistance: the CARDIA studyAnnals of Epidemiology, 2004
- The International HapMap ProjectNature, 2003
- Uncoupling Protein-2 Negatively Regulates Insulin Secretion and Is a Major Link between Obesity, β Cell Dysfunction, and Type 2 DiabetesCell, 2001
- The association between the val/ala-55 polymorphism of the uncoupling protein 2 gene and exercise efficiencyInternational Journal of Obesity, 2001
- Impact of the v/v 55 polymorphism of the uncoupling protein 2 gene on 24‐h energy expenditure and substrate oxidationInternational Journal of Obesity, 1999
- Association between uncoupling protein polymorphisms (UCP2-UCP3) and energy metabolism/obesity in Pima indiansHuman Molecular Genetics, 1998
- Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemiaNature Genetics, 1997
- Cardia: study design, recruitment, and some characteristics of the examined subjectsJournal of Clinical Epidemiology, 1988