Safety and Efficiency of Ergotamine Tartrate and Dihydroergotamine in the Treatment of Migraine and Status Migrainosus [RETIRED]

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Abstract
Justification. Migraine is a very common and frequently disabling neurologic disorder. Recent estimates indicate that more than 23 million Americans currently experience migraine headache; 11 million report at least some headache-related disability [1]. About one-third of migraineurs in the United States report severe disability or the need for bed rest with their attacks [1,2]. However, the majority of migrain sufferers in the United States have never actually been diagnosed as having migraine [3], nor do they take prescription drugs [4].