The Involvement of RNA in Protein Synthesis

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Abstract
IN 1940 the work of Beadle and Tatum1 established the concept that the genes carry out their function by controlling specific proteins. At approximately the same time Brachet2 and Caspersson3 independently concluded that ribonucleic acid (RNA) was somehow associated with protein synthesis. In the next fifteen years, several major advances were made: DNA was identified as the genetic material4; its double helical structure was elucidated5; it was postulated that DNA carries information as a sequence of nucleotide bases, from which a complementary copy can be made6; and the ribosomes, containing most of the cell's RNA, were identified . . .

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