Diffusion Tensor MR Imaging in Diffuse Axonal Injury

  • 1 May 2002
    • journal article
    • Vol. 23  (5) , 794-802
Abstract
BACKGROUND AND PURPOSE: Disruption of the cytoskeletal network and axonal membranes characterizes diffuse axonal injury (DAI) in the first few hours after traumatic brain injury. Histologic abnormalities seen in DAI hypothetically decrease the diffusion along axons and increase the diffusion in directions perpendicular to them. DAI therefore is hypothetically associated in the short term with decreased diffusion anisotropy. We tested this hypothesis by measuring the diffusion characteristics of traumatized brain tissue with use of diffusion tensor MR imaging.

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