Abnormal Brain Diffusivity in Patients with Neuropsychiatric Systemic Lupus Erythematosus
- 1 May 2003
- journal article
- Vol. 24 (5) , 850-854
Abstract
BACKGROUND AND PURPOSE: Neuroimaging techniques have increased our knowledge of the pathogenesis of neuropsychiatric systemic lupus erythematosus (NPSLE) and have been useful in supporting the diagnosis. Nevertheless, new imaging techniques are needed to unravel the exact pathogenesis and to provide diagnostic criteria for NPSLE. In this preliminary study, we investigated whether diffusion-weighted imaging (DWI) can depict cerebral abnormalities in patients with a history of NPSLE, and we assessed whether apparent diffusion coefficient (ADC) histograms in these patients differ from those of healthy control subjects.Keywords
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