Immunohistochemical Demonstration of a Testicular Substance Related to Luteinizing Hormone-Releasing Hormone

11 September 1981

journal article
research article
Published by American Association for the Advancement of Science (AAAS) in Science

Vol. 213 (4513) , 1263-1264
https://doi.org/10.1126/science.7022653

Abstract

A substance related to luteinizing hormone-releasing hormone was demonstrated, by immunohistochemical procedures, in the cytoplasm of interstitial cells within the rat testes. In many seminiferous tubules, nuclei of spermatogonial cells were also immunopositive. Both cytoplasmic and nuclear fractions of testicular homogenates contain immunoreactive compounds, and this report identifies which cell types contain this substance. The localization of a peptide hormone within the nucleus of a target cell population may indicate its mode of action.

Keywords

MODE OF ACTION

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