Segment-specific expression of the gap junction gene connexin31 during hindbrain development
- 1 November 1997
- journal article
- expression note
- Published by Springer Nature in Wilhelm Roux' Archiv für Entwicklungsmechanik der Organismen
- Vol. 207 (5) , 359-361
- https://doi.org/10.1007/s004270050123
Abstract
During segmentation of the mouse hindbrain (d8.0–8.5 pc), expression of the gap junction gene connexin31 (cx31) is precisely restricted to rhombomeres (r) 3 and 5. Shortly afterwards, during the turning process, cx31 expression in rhombomere 3 decreases and is no longer detectable at d9.5 pc, whereas expression in rhombomere 5 is maintained until about d10.0 pc. So far, cx31 is the first gap junction gene found to be expressed in rhombomeres. Its precise segmental and temporal expression pattern may reflect a critical requirement of cx31 channels for these odd numbered rhombomeres to acquire distinct cell identities.Keywords
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