Prodrugs as drug delivery systems. 107. Synthesis and chemical and enzymatic hydrolysis kinetics of various mono- and diester prodrugs of N-acetylcysteine
- 1 July 1990
- journal article
- research article
- Published by Elsevier in International Journal of Pharmaceutics
- Vol. 62 (2-3) , 193-205
- https://doi.org/10.1016/0378-5173(90)90233-t
Abstract
No abstract availableKeywords
This publication has 28 references indexed in Scilit:
- Enhanced delivery of nalidixic acid through human skin via acyloxymethyl ester prodrugsInternational Journal of Pharmaceutics, 1989
- Effect of N-acetylcysteine on plasma cysteine and glutathione following paracetamol administrationEuropean Journal of Clinical Pharmacology, 1989
- Glycolamide esters as a novel biolabile prodrug type for non-steroidal anti-inflammatory carboxylic acid drugsInternational Journal of Pharmaceutics, 1988
- Gastrointestinal metabolism of N‐acetylcysteine in the rat, including an assay for sulfite in biological systemsBiopharmaceutics & Drug Disposition, 1987
- Methodologies for the analysis of reduced and oxidized N‐acetylcysteine in biological systemsBiopharmaceutics & Drug Disposition, 1987
- Pharmacokinetics of N-acetylcysteine in manEuropean Journal of Clinical Pharmacology, 1986
- Prodrugs of 5-fluorouracil. I. Hydrolysis kinetics and physicochemical properties of various N-acyl derivatives of 5-fluorouracilInternational Journal of Pharmaceutics, 1984
- Chlorosulfates as Reagents in the Synthesis of Carboxylic Acid Esters Under Phase-Transfer ConditionsSynthetic Communications, 1984
- Biologically oriented organic sulfur chemistry. VI. Uses of o-carboxyphenyl o-carboxybenzenethiosulfonate with thiolsThe Journal of Organic Chemistry, 1971
- Dithiothreitol, a New Protective Reagent for SH Groups*Biochemistry, 1964