Early fine structural changes in human epidermis following application of croton oil
Open Access
- 1 January 1978
- journal article
- research article
- Published by Medical Journals Sweden AB in Acta Dermato-Venereologica
- Vol. 58 (1) , 31-35
- https://doi.org/10.2340/00015555583135
Abstract
Early epidermal changes in human subjects following application of 10% croton oil in acetone were studied by electron microscopy. The prominent changes observed at 1 and 5 hours were degeneration of epidermal cells and intercellular edema in the basal and spinous layers. One type of degeneration was homogenization and aggregation of the tonofilaments of keratinocytes at 1 hour, which may explain the presence of dyskeratotic cells at 5 hours. Another type was of a cytolytic nature as evidenced by severe perinuclear edema of keratinocytes and destruction of Langerhans' cells with outpouring of Birbeck's granules in the intercellular spaces.This publication has 1 reference indexed in Scilit:
- Early changes in human epidermis following thermal burn: an electron microscopic studyActa Dermato-Venereologica, 1977