Characterization and regulation of pre-ovulatory secretion of gonadotrophin-releasing hormone

Abstract
Using an elegant method for sampling of pituitary portal blood the secretory characteristics of gonadotrophin-releasing hormone (GnRH) during the oestradiol induced surge are studied. It is demonstrated that the neuroendocrine signal for ovulation in the ewe is a surge of GnRH released into the portal blood.

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