Profilin acts downstream of LDL to mediate diabetic endothelial cell dysfunction
Open Access
- 20 February 2004
- journal article
- fj express-summaries
- Published by Wiley in The FASEB Journal
- Vol. 18 (6) , 725-727
- https://doi.org/10.1096/fj.03-0841fje
Abstract
The changes occurring at the luminal surface of endothelial cells in diabetes and their relevance to endothelial dysfunction are poorly characterized in vivo. In this study, we developed an integrate...Keywords
This publication has 47 references indexed in Scilit:
- Dynamic interaction of VCAM-1 and ICAM-1 with moesin and ezrin in a novel endothelial docking structure for adherent leukocytesThe Journal of cell biology, 2002
- High Glucose-altered Gene Expression in Mesangial CellsJournal of Biological Chemistry, 2002
- Bax Is Increased in the Retina of Diabetic Subjects and Is Associated with Pericyte Apoptosis in Vivo and in VitroThe American Journal of Pathology, 2000
- Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34)The Lancet, 1998
- Analysis and Regulation of Vasodilator-stimulated Phosphoprotein Serine 239 Phosphorylation in Vitro and in Intact Cells Using a Phosphospecific Monoclonal AntibodyJournal of Biological Chemistry, 1998
- Leukocyte-endothelial interaction is augmented by high glucose concentrations and hyperglycemia in a NF-kB-dependent fashion.Journal of Clinical Investigation, 1998
- A Role for Src in Signal Relay by the Platelet-derived Growth Factor α ReceptorJournal of Biological Chemistry, 1998
- Organ targeting In vivo using phage display peptide librariesNature, 1996
- Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cellsPublished by Elsevier ,1992
- Actin polymerizability is influenced by profilin, a low molecular weight protein in non-muscle cellsJournal of Molecular Biology, 1977